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GLP-1R modulator L7-028
CAS No. 2648317-95-5
GLP-1R modulator L7-028( —— )
Catalog No. M35193 CAS No. 2648317-95-5
GLP-1R modulator L7-028 is a variant that enhances affinity for GLP-1 and (cAMP) signaling.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | Get Quote |
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| 5MG | 132 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameGLP-1R modulator L7-028
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NoteResearch use only, not for human use.
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Brief DescriptionGLP-1R modulator L7-028 is a variant that enhances affinity for GLP-1 and (cAMP) signaling.
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DescriptionGLP-1R modulator L7-028 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetGlucagon Receptor
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RecptorGlucagon Receptor | cAMP
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Research Area——
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Indication——
Chemical Information
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CAS Number2648317-95-5
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Formula Weight392.49
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Molecular FormulaC24H28N2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (254.78 mM; Ultrasonic )
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SMILESO=C(Nc1cccc(c1)C(=O)N1CCCCC1)c1cccc(OC2CCCC2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang J, et al. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS Chem Biol. 2021 Nov 19;16(11):2444-2452. ?
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Semaglutide
Semaglutide has two amino acid substitutions compared to human GLP-1 (Aib8, Arg34) and is derivatized at lysine 26.
